Include information about the disease and its symptoms
Pertussis, otherwise known as the whooping cough or the 100-day cough, is a highly contagious bacterial disease in which the patient suffers from severe coughing fits, after which a high pitched “whoop” sound or gasp may occur as a patient breathes. These coughing fits can become so extreme that they can cause the patient to vomit, break ribs, and experience extreme fatigue from the effort of coughing. People suffering from Pertussis may also lose weight and lose control of their bladder.
Pertussis in babies under the age of one is extremely dangerous and can be deadly, the baby has little to no cough but instead will have apnea, in which the baby goes through periods of time where they
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Gram-negative bacteria contain a layer of lipopolysaccharide (LPS) When the bacteria enters the body, the LPS triggers the body’s immune response. The body recognises a cytokine reaction from the bacteria which is toxic to the body and responds by inflaming the tissues and blood vessels. The certain cells used against the bacteria Bordetella Pertussis include innate and specific defenses, but the defensive antigens have not been exclusively identified.
Explain how the disease can be treated.
Pertussis is generally treated with antibiotics and it is vital to use the antibiotics early on in the infection or it will have little to no effect. Antibiotics work best before the coughing fits begin because after three weeks the bacteria Bordetella Pertussis would have already damaged the body and left. Taking antibiotics in the early stages of Pertussis can help stop the disease from spreading in close
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A vital way Pertussis is prevented is through vaccines. There are two types of Pertussis vaccines, whole-cell vaccine (wP) and acellular Pertussis (aP) There is little difference between the vaccines as the efficiency in defence against Pertussis are similar and the adverse effects are minor in both vaccines, the main difference is the price. aP vaccines are commonly used in developed countries because people can afford them, whilst in developing countries wP is the preferred vaccine because of the low prices.
The human immune response against wP vaccines is directed against an array of antigens of the whole bacterial cells. Some antigens like Pertussis Toxins (PT) have been recorded as “immune response modifiers” There are also records of substantial disparities in immune responses depending on the antigens found in different vaccines that were tested.
The human immune response against aP vaccines are directed against “purified protein virulence factors” it was also said by ‘Decker & Edwards’ that “Significant differences in immunogenicity per µg protein between different vaccines have been
The vaccines are then injected into the body, where the immune system will see the virus and kill it. Since this virus was already in the body once, the antibodies will remember it and attack it, preventing you from getting sick. A lot of other well-known vaccinations were discussed in this book, however, not all of them came from the WI-38 cell line. Dr. Hayflick also discovered the MRC-5 cell line which was developed from fetal lung tissue. The vaccine for Hepatitis A was developed by the MRC-5 cell line where the incubated virus is purified and then weakened just like the WI-38 cell
Polio (also known as poliomyelitis) is an infectious virus that causes paralysis and sometimes death in people infected by it. Polio is also extremely contagious, able to infect people through person to person contact and unsanitary conditions. The polio vaccine was originally created by Dr. Jonas Salk in the 1950s, and was shown to be 90% effective against types II and III polio, and 70% effective against type I polio. Because of the vaccines effectiveness, the United States government set a goal to vaccinate 30,000 children by the July of 1955.
Those against mandatory vaccines deem that the chickenpox, measles, rubella and rotavirus all have symptoms that can be treated with oral medicines and creams. Vaccine-preventable diseases have not disappeared so vaccination is still necessary and the diseases that decreased tremendously were due to the impact of vaccines. The CDC notes that many vaccine-preventable diseases are still in the United States or "only a plane ride away." Although the paralytic form of polio has largely disappeared thanks to vaccination, the virus still exists in countries like Pakistan where there were 93 cases in 2013 and 71 in 2014 as of May 15. The polio virus can be incubated by a person without symptoms for years; that person can then accidentally infect an unvaccinated child or adult in whom the virus can mutate into its paralytic form and spread amongst unvaccinated people.
However the real victims in danger are infants, “who are typically hospitalized [due to the fact that] whooping cough is more dangerous in that age group” (Treatments and Drugs). Some cures or home remedies would be to get plenty of sleep, and drink plenty of liquids. One way of preventing viruses is by, “practicing good hygiene to prevent the spread of [a] respiratory illness” (Prevention). Other ways of preventing pertussis are by getting vaccinated. There are many types of vaccines for pertussis, “in the U.S. DTap, Tdap and Td vaccines are most commonly used” (Vaccine Information).
One of the many benefits of vaccinating children is it saves them from life-threatening diseases. The many diseases which children are immunized from include, Measles, Mumps, Tetanus, Diphtheria, Pertussis (whooping cough), Polio, Hepatitis A and B and much more. Long before the time of vaccines, there was a shocking rate of deaths that occurred worldwide.
Since infants and young children are very vulnerable and lack independence, healthy physical development is dependent on protecting them from outside harms. Vaccines protect not just the child being vaccinated but also other children who may not be vaccinated. Some children cannot receive vaccines due to health conditions, such as child with allergies or a deficient immune system. These children are at risk for catching devastating illnesses when they come in contact with unvaccinated children. When parents have their children vaccinated it is good for the health of both the vaccinated children and other children in the
The flu vaccine is the most common vaccination, most likely because it changes every year and can be spread so easily. DTap (Diphtheria, Tetanus, and Pertussis) is designed to help develop immunity for children who are 7 or younger. These diseases can be very harmful, so the less likely one is to develop one of these illnesses, the better. Most people should get the IPV vaccine, which was developed in 1955, due to the many different cases of polio. Children should receive four different doses of this vaccine throughout their life.
The influenza pandemic was devastating among those infected and was responsible for the death of 675,000 Americans and 50 million people all over the world in 1918. As a result of this devastation, vaccines were formulated to prevent future outbreak of deadly and viral diseases, some becoming required by law. However, today many people have decided to boycott any form of vaccination whether it be for their children, or even their pets, due to the modern theory that they may weaken new immune systems. History has proven over time that vaccinations are absolutely effective in preventing dangerous strains of illnesses while saving countless lives since their creation and should be given to all children and at-risk adults.
Today, young children receive vaccines to protect them against 14 different diseases. Because some vaccines require more than one dose, children can receive as many as 26 inoculations by 2 years of age and up to five shots at one time. For this reason, some parents now ask their doctors to space out, separate or withhold vaccines. If the parent(s) decided to not vaccinate their child, the child may not have the necessary antibodies to fight off infection. That is why to protect the child, the vaccine needs to be not enforced on the child, but strongly suggested by the doctor.
Vaccines are like traffic lights; they ensure the safety of the public, be in heavily crowded areas, like schools, or densely trafficked roads. Traffic lights only work when all people follow the rules. If a car runs a red light, the car runs the risk of killing innocent pedestrians who are complying with the prescribed rules. Vaccines, if not utilized by most people, are ineffective. Even though some parents are concerned over the safety of vaccines, children who go to public schools should not be granted exemptions because vaccines are necessary to prevent outbreaks, children who do not receive vaccines are at risk of disease, and medically compromised children rely on vaccines to prevent disease.
No medicine is perfect, of course, but most childhood vaccines produce immunity about
Vaccinations When it comes to vaccinations, there are many different opinions on immunizing a child, especially when that child’s parent has a strong like or dislike towards vaccinating. Immunizations have existed for at least a thousand years and as technology advances more, there are new vaccines being designed to help protect our children from contracting contagious and sometimes deadly diseases, such as Bordetella pertussis, polio, and even influenza. For decades, all 50 states have required that parents vaccinate their children against various diseases, including polio and measles, as a prerequisite to enrolling them in public schools (Ciolli, 2008). Enrollment in public school requires up to date vaccinations in order to protect the children and even the adults from contracting and spreading a disease, possibly causing an epidemic.
Pediatric pneumonia is the most common cause of mortality in children. Although , there are cures for this infection , if not detected early , it can pose to be life threatening. Most cases of pediatric pneumonia are found in developing countries like Bangladesh , Nigeria and the Sub Saharan Region. According to WHO , as of 2013 , the causality rate caused by pneumonia is at 2 million, amongst children under the age of five. This dramatically rising number proves that there is a need to understand the etiology of this infection , and determine what factors can be assessed to help in early detection of pneumonia.
In order for vaccines to work appropriately, they have to operate in a very convoluted way to make sure they live up to their standards. 1. Vaccines are developed by using the bacteria’s specimen that has been either killed or damaged which are dissolved in a solution. When the vaccine is injected into the body, the specimen revives that person’s immune system. After being injected, the immune system will now fight against the microbe by forming antibodies.
Pneumonia is a frequent cause of hospitalization and illness amongst children, with incidence of 4% per year under the age of 5, 2% per year in children 5-9 years of age and 1% per year in older children and adolescents.[1] Out of these a small number of patients develop persistent and recurrent pneumonia, which presents a big challenge for physicians to manage and diagnose. A proper approach to face this challenge first requires a proper definition of the term recurrent pneumonia. Pneumonia is as an acute illness characterized by cough, fever and tachypnoea in a generally unwell child, with labored breathing or abnormalities (bronchial or diminished breath sounds or crackles) on chest auscultation.[2] Recurrent pneumonia is defined as two or more episodes of pneumonia in a year, or three or more ever, with radiographic clearing between occurrences, and is reported in 7–9% of children with pneumonia.[3,4] It is common practice to investigate the immune and respiratory systems in children with recurrent pneumonia.[3,4]