Cystic Fibrosis: A Genetic Disease

Black lung is a common name for any lung disease that results from inhaling coal dust. Anthracosis, commonly known as “Black Lung” or “Coal Miner’s Pneumoconiosis, is a common problem in the area in which we live, The Appalachian Mountains. The Appalachians are full of coal mines making Black Lung very common in our area. Not only has this disease common in the eastern part of the United States, it has become prevalent across the whole country and world. Every year there is roughly 1,000 deaths over the course of the year.

Definition of Net Neutrality. Network Neutrality. Retrieved from https://www.ocf.berkeley.edu/~raylin/whatisnetneutrality.htm The Pros and Cons of Net Neutrality. Phil for Humanity.

Cystic fibrosis What is cystic fibrosis? Cystic fibrosis is genetic disorder characterized by abnormal chloride channels. This characteristically results in disease affecting multiple organ systems, most notably the lungs and gastrointestinal tract. Lung disease is usually manifested as obstructive lung disease due to bronchiectasis.

These diseases are all genetic, making Jews’ genetic make-up very similar. The genes are so similar that people could argue that Judaism is a race. These genetic diseases are in certain groups. There are lysosomal storage diseases, glycogen storage diseases, clotting factor deficiencies, steroid hormone biosynthetic defects, and DNA mutations causing cancers. The lysosomal storage diseases are Tay-Sachs disease, Niemann-Pick disease, Gaucher disease and Mucolipidosis IV.

Another problem that CF patients face is that it is extremely difficult to be in any sport. If a CF patient plays a sport, it would be very difficult to breath throughout the time. It 's like breathing through one of those black coffee stirring straws. CF makes life in all aspects very difficult. Any sort of travel is very complicated and difficult.

Although the disorders beneath this condition aren't completely inherited, they might have a small family inheritance. You won't locate this disorder in the healthcare books. It's a disorder of the intestines where the large intestine doesn't function adequately. This form of syndrome is a life threatening and has to be treated appropriately. The reason for the syndrome is unknown, but researchers think that disruption of the development of the fetus leads to the problems to develop.

Cystic fibrosis (CF) is an inherited disease that affects the secretory system. A defective gene has to be inherited from both parents for a child to have the disease. CF is usually diagnosed at a young age. It is one of the most common chronic lung diseases in children; thankfully, treatments for this disease have improved over the years (Parker-Pope). Cystic fibrosis affects many parts of a person’s life; there are many symptoms, treatments, and social effects of this disease.

The human genetic disorder that I selected is Cystic Fibrosis. Cystic fibrosis is a common genetic disease within the white population in the U.S. Genetic human reference describes it as an inherited disease characterized by the buildup of thick, sticky mucus that can damage many of the body’s organs. Common signs and symptoms are progressive damage to the respiratory system and digestive system. Mucus is usually a thin slippery substance that lubricates and protects linings of organs and tissues. Cystic fibrosis deals with mutations in the CFTR gene.

(n.d.). Definition of Conditioned . Retrieved from www.chegg.com: http://www.chegg.com/homework-help/definitions/conditioned-vs-unconditioned-response-13 psychology.about.com. (n.d.).

The authors also came up with the “multiple hit” model to explain and understand the pathogenesis of IPF. This model proposes that IPF is more a result of a combination of genetics and multiple environmental ‘hits’ that eventually leave the Type II alveolar epithelial cells susceptible to development of lung scarring and modification of the lung architecture. The Seibold et.al, 2011 study has theorized, as one of three possibilities, that the MUC5B mutation damages the mucosal host resistance mechanism causing disproportionate lung scarring and eventually leading to an advance of idiopathic interstitial pneumonia. According to the ‘multiple hit’ theory, the occurrence of interstitial pneumonia and GERD will eventually lead to scarring of the lungs and the subsequent outbreak of

It affects mainly the small bowel and can be caused by either viral or bacterial INFECTION” (Ignatavicius and Workman, 2016, p.1127). One of the largest barriers to treatment of a C.diff infection is the resistance to antibiotics. The CDC (2016) says “C.difficile caused almost half a million infections among patients in the United States in a single year. An estimated 15,000 deaths are directly attributable to C.difficile infections” (clostridium difficile section, para. 2) .

" This means that this genetic disorder normally skips a generation and your daughter may inherit this disorder if both the husband and wife have

Cystic Fibrosis is a common and inherited disorder of the respiratory system. A mutation of the cystic fibrosis transmembrane regulator gene causes cystic fibrosis. This gene is located on chromosome seven, and this chromosome manages a chloride channel found in the tissues of the exocrine. If the channel is blocked, then thick secretion will build up in the lungs, and other organs and it will be extremely hard to eliminate. This can lead to severe issues, or even death.

Cystic fibrosis (CF) is a genetic disease that affects secretory glands throughout the body, gravely affecting the respiratory system and other systems. A body affected by CF produces unusually thick and sticky mucus that creates infection and accumulates in various pathways (Grossman and Grossman, 2005). This is caused by a defect in a membrane protein called the Cystic Fibrosis Transmembrane Regulator (CFTR), which is due to a mutation in the CFTR gene (Freedman and O’ Sullivan, 2009). The CFTR protein is an ATP-dependent ion channel that allows the movement of chloride ions across epithelial cells, helping to maintain fluid balance via osmosis (Miller et al., 2005). In a mucus-producing cell, the CFTR protein allows chloride ions to enter

Asthma is developed by a biological reaction to a foreign substance involving cellular foreign substance involving cellular recognition of (and memory for) that specific substance1. Factors such as eczema, hay fever, smoking, working in an environment with a lot of air pollution and a family history of the disease are common findings in patients who suffer from asthma, and are thought be the cause for the development of the disease2. This may be due to the irritation that these factors place on the respiratory system. This causes the bronchioles of the lungs to constrict (bronchoconstriction), and the smooth muscle that controls the bronchioles to spasm (bronchospasm), therefore the airway is narrowed, and delivery of air to the lungs is restricted1.